Male infertility is defined as the inability to cause a pregnancy after one year of regular, unprotected intercourse. It is a common health concern that affects many couples in Singapore and around the world. The causes are varied, and a diagnosis does not mean that starting a family is impossible.
This guide explains the causes of male infertility, how it is diagnosed by healthcare professionals, and the different treatment options that are available to help individuals and couples understand their reproductive health and plan their next steps.
What Is Male Infertility?
Infertility is a condition of the reproductive system that prevents the conception of children. When the issue is traced back to the male partner, it is referred to as male infertility. It is important to understand that fertility is a shared health concern for a couple.
For about half of all couples who struggle to conceive, male factor infertility plays a role, either as the sole cause or in combination with female factor infertility. Therefore, when a couple seeks medical advice for conception difficulties, investigations typically involve both partners to get a complete picture of their combined reproductive health.
What Causes Male Infertility?

The causes of male infertility can be complex and are often grouped into medical, lifestyle, and environmental factors. In some instances, a clear cause cannot be identified. A thorough medical evaluation is necessary to determine the specific factors contributing to a man’s fertility issues.
Medical Causes
Several medical conditions can interfere with sperm production, its function, or the pathways sperm use to travel out of the body. These are among the most common reasons for male infertility.
Problems with how the testicles produce sperm can lead to a low sperm count, known as oligospermia, or a complete absence of sperm, known as azoospermia. Issues can also arise with the sperm’s ability to move effectively (motility) or its shape (morphology), both of which are crucial for fertilising an egg.
A varicocele is a swelling of the veins that drain the testicle, similar to a varicose vein you might see in a leg. This is a common cause of male infertility. The swollen veins can raise the temperature in the scrotum, which can negatively affect sperm production and quality.
Certain infections can interfere with sperm production or sperm health, or they can cause scarring that blocks the passage of sperm. This includes infections of the epididymis (epididymitis) or testicles (orchitis). Some sexually transmitted diseases (STDs), such as chlamydia and gonorrhoea, can also lead to blockages in the reproductive tract if left untreated, preventing sperm from being part of the ejaculate.
Hormones produced in the pituitary gland and testicles are essential for sperm development. An imbalance in hormones like testosterone and others can significantly disrupt sperm production. This can be caused by disorders of the testicles themselves or an issue with the glands that regulate them.
The tubes that carry sperm from the testicles can become blocked, preventing sperm from leaving the body during ejaculation. These blockages can result from previous surgeries, such as a vasectomy, prior infections, or developmental issues from birth.
Some individuals may have genetic conditions that affect their fertility. Chromosomal disorders can cause abnormal development of the male reproductive organs or issues with sperm production. These genetic factors can be passed down or occur randomly.
Lifestyle and Environmental Factors
A person’s daily habits and environment can have a significant impact on their reproductive health. Many of these factors are modifiable, meaning that positive changes can help improve fertility potential.
Using tobacco, drinking excessive amounts of alcohol, or using illicit drugs can lower sperm count and affect sperm quality. These substances can interfere with hormone production and directly damage sperm cells.
Being significantly overweight or obese can alter hormone levels and negatively impact fertility. Excess body fat can lead to an increase in oestrogen and a decrease in testosterone, which is not ideal for sperm production.
The testicles are located outside the body for a reason: they need to be slightly cooler than the core body temperature to produce sperm effectively. Frequent use of saunas, hot tubs, or even wearing very tight underwear can raise the scrotal temperature and temporarily reduce sperm production.
Prolonged exposure to certain industrial chemicals, pesticides, heavy metals, or radiation can reduce sperm production or damage sperm DNA. Men whose work involves exposure to these elements should follow safety guidelines to minimise their risk.
Recognising The Signs And Symptoms Of Male Infertility

For most men, the main and sometimes only sign of infertility is the inability to conceive a child with their partner. There are often no other obvious signs or symptoms. However, in some cases, an underlying health problem might cause other noticeable symptoms.
These can include problems with sexual function, such as difficulty maintaining an erection (erectile dysfunction) or issues with ejaculation. Some men may experience pain, swelling, or a lump in the testicle area, which should always be checked by a doctor.
Other less common signs that might point to a hormonal issue include a decrease in facial or body hair or abnormal breast growth, known as gynaecomastia. If a man experiences any of these symptoms alongside difficulties conceiving, it is important to seek a medical consultation.
The Process of Diagnosing Male Infertility
A diagnosis of male infertility starts with a visit to a doctor. The process is systematic and designed to identify any underlying causes, helping to guide the most appropriate course of action.
Initial Consultation and Medical History
The first step is a detailed discussion with your doctor. They will ask about your general health, any past illnesses or surgeries, and your family’s medical history. You will also be asked about your lifestyle, such as your diet, exercise habits, and whether you smoke or drink alcohol.
Questions about your sexual history and current sexual habits are also a standard and important part of the evaluation to understand the full context of the fertility issue. This will be followed by a general physical examination, which includes an examination of the genital area to check for any physical abnormalities.
Semen Analysis
A semen analysis is a fundamental test in evaluating male fertility. You will be asked to provide a semen sample, which is then analysed in a laboratory. This test provides crucial information about your sperm. The main parameters checked are:
- Sperm Count: This measures the number of sperm in your ejaculate. A lower-than-normal count may affect the chances of fertilisation.
- Sperm Motility: This assesses how well your sperm are moving. Sperm need to be able to swim effectively to travel through the female reproductive tract and reach the egg.
- Sperm Morphology: This examines the size and shape of your sperm. Abnormally shaped sperm may be less able to fertilise an egg.
You may be asked to provide more than one sample over a period of time, as sperm count and quality can vary from day to day.
Further Diagnostic Tests
Depending on the results of your initial consultation and semen analysis, your doctor may recommend further tests to get more information. A blood test can be used to check the levels of testosterone and other hormones that play a role in sperm production.
A scrotal ultrasound uses sound waves to create images of the inside of the scrotum, allowing the doctor to look for conditions like varicoceles or blockages in the testicles. A urinalysis, which is a test of your urine, may be performed after ejaculation to see if sperm are travelling backwards into the bladder instead of out of the penis, a condition known as retrograde ejaculation.
Since untreated infections can cause infertility, screening for STDs is also an important part of a comprehensive diagnostic process.
Treatment Options for Male Infertility

Once a diagnosis is made, your doctor can recommend treatment options. The right approach depends on the underlying cause of infertility, your overall health, and your personal preferences.
Lifestyle Adjustments
For some men, making changes to their daily habits can have a positive effect on fertility. This can include quitting smoking, reducing alcohol intake, and avoiding recreational drugs. Achieving and maintaining a healthy weight through a balanced diet and regular exercise can also improve hormone levels and sperm quality. It is also advisable to avoid activities that overheat the testicles, such as frequent use of hot tubs or saunas.
Medications
Medications can be an effective treatment for certain causes of male infertility. For example, if an infection is affecting your reproductive tract, your doctor will prescribe antibiotics. If the issue is related to a hormonal imbalance, hormone treatments may be recommended to help restore normal sperm production. Medications may also be used to treat conditions like erectile dysfunction or problems with ejaculation.
Surgical Procedures
In some cases, surgery may be an option to correct a physical problem that is causing infertility. A varicocele can be surgically repaired in a procedure that blocks off the abnormal veins, which can improve sperm quality.
If there is a blockage in the tubes that transport sperm, a surgical procedure can sometimes correct it. For men who have previously had a vasectomy, a vasectomy reversal surgery can be performed to reconnect the tubes.
Assisted Reproductive Technology (ART)
Assisted Reproductive Technology (ART) refers to a range of medical procedures used to help with conception. These techniques can be very effective, especially when other treatments have not been successful.
Intrauterine insemination (IUI) is a procedure where specially prepared sperm is placed directly into the partner’s uterus around the time of ovulation. In vitro fertilisation (IVF) involves retrieving eggs from the female partner and fertilising them with sperm in a laboratory.
The resulting embryo is then transferred to the uterus. A technique often used with IVF, especially in cases of severe male infertility, is intracytoplasmic sperm injection (ICSI). This procedure involves injecting a single healthy sperm directly into a mature egg.
Conclusion On Male Infertility
Male infertility is a common health issue that affects many couples, but it is important to remember that there are many paths to building a family. The causes are diverse, ranging from medical conditions to lifestyle factors.
The first and most crucial step is seeking a proper diagnosis from a qualified healthcare professional. With a clear understanding of the underlying issue, many effective treatment options are available to improve fertility or assist with conception. A confidential discussion with a doctor can provide clarity and help you explore the best way forward.
Our experienced team of healthcare professionals specialises in diagnosing and treating sexually transmitted diseases. From same-day STD testing to homebased health screening, we deliver accurate and reliable care tailored to your needs.
Frequently Asked Questions About Male Infertility
What Is the Main Cause of Male Infertility?
There is not one single main cause of male infertility, as it can result from a variety of factors. Most commonly, it stems from issues with sperm production or the delivery of sperm. This can include a low sperm count, poor sperm movement (motility), or abnormally shaped sperm (morphology). Underlying medical conditions like varicoceles, infections, hormonal imbalances, and certain lifestyle choices can all contribute to these issues.
What Are the Signs of Being Infertile for a Man?
The most definite sign of infertility in a man is the inability to conceive a child with a partner after one year of regular, unprotected intercourse. In many cases, there are no other obvious symptoms. However, some men might experience signs related to an underlying issue, such as problems with sexual function, pain or swelling in the testicle area, or changes in hair growth, which could indicate a hormonal imbalance.
How Can I Check My Fertility as a Man?
The most reliable way to check your fertility is to consult a doctor. The primary test is a semen analysis, where a sample is examined in a laboratory to assess your sperm count, movement, and shape. A doctor will also conduct a physical examination and may recommend blood tests to check your hormone levels. This comprehensive approach provides an accurate picture of your reproductive health.
Can Male Infertility Be Cured?
In many situations, the specific cause of male infertility can be treated, which can help restore fertility. For instance, surgery can correct a physical issue like a varicocele or a blockage, and medication can effectively treat infections or correct hormone imbalances. Even if a cause cannot be completely “cured,” advanced treatments like Assisted Reproductive Technology (ART) can often help a couple achieve a successful pregnancy.
Can a Man With Zero Sperm Count Get a Woman Pregnant?
A man with zero sperm in his ejaculate, a condition called azoospermia, cannot get a woman pregnant through natural intercourse. However, it may still be possible for him to have a biological child. In certain cases of azoospermia, sperm can be surgically retrieved directly from the testicles. These retrieved sperm can then be used in a laboratory to fertilise an egg through a process known as IVF with ICSI.
At What Age Do Men Become Less Fertile?
Men can produce sperm for most of their lives, but male fertility does begin to decline with age. This gradual decline typically starts around the age of 40 to 45. As a man gets older, the quality and motility of his sperm tend to decrease. There is also a slightly higher risk of genetic abnormalities in the sperm with increasing paternal age.


